{"id":7804,"date":"2024-07-05T12:18:42","date_gmt":"2024-07-05T08:48:42","guid":{"rendered":"https:\/\/epacogroup.com\/en\/?p=7804"},"modified":"2024-08-13T12:41:06","modified_gmt":"2024-08-13T09:11:06","slug":"vitamin-b9-folic-acid","status":"publish","type":"post","link":"https:\/\/epacogroup.com\/en\/vitamin-b9-folic-acid\/","title":{"rendered":"Vitamin B9 (Folic Acid)"},"content":{"rendered":"<section class=\"l-section wpb_row height_small\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><h3 class=\"w-text us_custom_2f45fd4a Vitamin\"><span class=\"w-text-h\"><span class=\"w-text-value\">Vitamin B9 (Folic Acid)<\/span><\/span><\/h3><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row matnzohor height_small\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column us_custom_51948308 has_text_color\"><div class=\"wpb_wrapper\"><p>Stokstad (1943) isolated folic acid as a result of investigations of the properties of factors present in yeast or liver that would promote the growth of lactic acid bacteria. Subsequent studies demonstrated that the active factor was identical to, or related to, antianemia factors and animal growth factors discovered by other investigators. Mowat et al., (1948) showed that folic acid is composed of a pteridine ring linked through a methylene bridge to p-aminobenzoic acid to form pteroic acid, which is in turn linked as an amide to glutamic acid. Early studies of the ability of purines or thymine to partially satisfy bacterial requirements for folic acid pointed to the involvement of this vitamin in purine and thymine biosynthesis. Early studies using\u00a0 14 C-labeled formate and formaldehyde suggested a role of folic acid in the metabolism of one-carbon units.<\/p>\n<p>Folic acid deficiency in chicks is characterized by poor feathering, anemic appearance (waxy white comb and pale mucous membranes in the mouth), lethargy, reduced feed intake, slow growth, and abnormal skeletal development leading to perosis.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner type_sticky\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/epacogroup.com\/en\/wp-content\/uploads\/2024\/03\/New-Project-13.webp\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/epacogroup.com\/en\/wp-content\/uploads\/2024\/03\/New-Project-13.webp 500w, 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Subsequent studies demonstrated that the active factor was identical to, or related to, antianemia factors and animal growth factors discovered by other investigators....","protected":false},"author":11,"featured_media":7986,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[65],"tags":[],"_links":{"self":[{"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/posts\/7804"}],"collection":[{"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/comments?post=7804"}],"version-history":[{"count":4,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/posts\/7804\/revisions"}],"predecessor-version":[{"id":8010,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/posts\/7804\/revisions\/8010"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/media\/7986"}],"wp:attachment":[{"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/media?parent=7804"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/categories?post=7804"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/epacogroup.com\/en\/wp-json\/wp\/v2\/tags?post=7804"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}